BDBM50602054 CHEMBL5209456

SMILES Fc1ccc(Oc2cc3sc(NC(=O)C4CC4)nc3cc2F)cc1NC(=O)Cc1cccc(c1)C(F)(F)F

InChI Key InChIKey=BQLWMSXWRKLECS-UHFFFAOYSA-N

Data  6 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50602054   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50602054(CHEMBL5209456)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to RIPK1 (unknown origin) by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50602054(CHEMBL5209456)
Affinity DataKd: >5.00E+6nMAssay Description:Binding affinity to RIPK3 (unknown origin) by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50602054(CHEMBL5209456)
Affinity DataKd:  15nMAssay Description:Binding affinity to recombinant RIPK1 (unknown origin) assessed as dissociation constant incubated for 1 hr by KINOMEscanTM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50602054(CHEMBL5209456)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to recombinant RIPK3 (unknown origin) assessed as dissociation constant incubated for 1 hr by KINOMEscanTM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50602054(CHEMBL5209456)
Affinity DataKd:  15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50602054(CHEMBL5209456)
Affinity DataKd: >5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed