BDBM50602058 CHEMBL5173634

SMILES CN1c2cc(ccc2OC[C@H](NC(=O)c2nc(Cc3ccccc3)n[nH]2)C1=O)C#CC1CC1

InChI Key InChIKey=QDIMLDKKJUQINI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50602058   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50602058(CHEMBL5173634)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of RIP1 (unknown origin) in ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50602058(CHEMBL5173634)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human RIPK1 (1-375) residues by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50602058(CHEMBL5173634)
Affinity DataIC50: 16nMAssay Description:Inhibition of human RIPK1 (1-375) residues by 33P-radiolabeled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed