BDBM50602100 CHEMBL5169346

SMILES COc1cc2ncnc3Nc4ccc(Cl)cc4OCCOCCOCCOc1cc23

InChI Key InChIKey=ZWNHCTNZGMTQTA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50602100   

TargetEpidermal growth factor receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50602100(CHEMBL5169346)
Affinity DataIC50: 16nMAssay Description:Inhibition of EGFR (unknown origin) Del19 mutant preincubated with compound 30 mins followed ATP addition incubated for 30 mins by HTRF KinEASE TK as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50602100(CHEMBL5169346)
Affinity DataIC50: 38nMAssay Description:Inhibition of EGFR (unknown origin) L858R mutant preincubated with compound 30 mins followed ATP addition incubated for 30 mins by HTRF KinEASE TK as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50602100(CHEMBL5169346)
Affinity DataIC50: 326nMAssay Description:Inhibition of EGFR (unknown origin) L858R/T790M mutant preincubated with compound 30 mins followed ATP addition incubated for 30 mins by HTRF KinEASE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50602100(CHEMBL5169346)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type EGFR (unknown origin) preincubated with compound 30 mins followed ATP addition incubated for 30 mins by HTRF KinEASE TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed