BDBM50602335 CHEMBL5186309

SMILES [H][C@@]12Cc3cc(Cl)c(Br)cc3C(=O)N1CCc1ccccc21

InChI Key InChIKey=KMFMHNWLVDMGHT-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50602335   

TargetAryl hydrocarbon receptor(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  3.20nMAssay Description:Activation of AhR in human HepG2 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual-luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  0.0580nMAssay Description:Activation of AhR in mouse NIH3T3 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual-lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  0.700nMAssay Description:Activation of AhR in human HaCaT cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual-luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  71nMAssay Description:Activation of AhR in mouse Hepa1c1c7 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed