BDBM50602865 CHEMBL5205974

SMILES COc1ccn2c(cc(C(=O)Nc3cc(cc(-c4cnn(C)c4)c3F)C(O)=O)c2c1)C(C)=O

InChI Key InChIKey=MQCYEERDINJMKD-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50602865   

TargetCREB-binding protein(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50602865(CHEMBL5205974)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of His6-tagged human CBP bromodomain (1081 to 1197 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCREB-binding protein(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50602865(CHEMBL5205974)
Affinity DataKd:  30nMAssay Description:Binding affinity to His6-tagged human CBP bromodomain (1081 to 1197 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed