BDBM50603611 CHEMBL5190336

SMILES Fc1ccc(cc1F)C#CC1=NC2=NC=NC2C(NCc2cccc(Cl)c2)=N1

InChI Key InChIKey=WEUICBIGFDONQO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50603611   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute (Ba, Mm, Sl, Sva)

Curated by ChEMBL
LigandPNGBDBM50603611(CHEMBL5190336)
Affinity DataEC50:  50nMAssay Description:Activation of human ABCG2-mediated ATPase activity preincubated for 2 mins followed by ATP addition and measured after 20 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed