BDBM50603682 CHEMBL5201888

SMILES CCc1nc(nc2cc(OC)c(cc12)-c1cnco1)[C@@H](N)CC(C)C

InChI Key InChIKey=HJFMOJJCYFCTLU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50603682   

TargetAP2-associated protein kinase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50603682(CHEMBL5201888)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human GST-Xa-tagged-AAK1 (30 to 330 residues) using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated for 3 hrs in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50603682(CHEMBL5201888)
Affinity DataIC50: 34nMAssay Description:Inhibition of full length human AAK1 expressed in HEK293F incubated for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed