BDBM50604083 CHEMBL5185921

SMILES Fc1ccc(NC(=O)N[C@@H](Cc2ccc(cc2)C#N)C(=O)N2Cc3ccccc3C2)cc1

InChI Key InChIKey=QCKGAEKQACBALR-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50604083   

TargetN-formyl peptide receptor 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50604083(CHEMBL5185921)
Affinity DataEC50:  340nMAssay Description:Agonist activity at human FPR2 transfected in human HL-60 cells assessed as increase in calcium mobilization measured every 5 seconds for 240 secs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetfMet-Leu-Phe receptor(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50604083(CHEMBL5185921)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human FPR1 transfected in human HL-60 cells assessed as increase in calcium mobilization measured every 5 seconds for 240 secs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetN-formyl peptide receptor 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50604083(CHEMBL5185921)
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at human FPR2 transfected in human HL-60 cells assessed as inhibition of WKYMVM-induced intracellular calcium mobilization preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetfMet-Leu-Phe receptor(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50604083(CHEMBL5185921)
Affinity DataIC50: 2.76E+4nMAssay Description:Antagonist activity at human FPR1 transfected in human HL-60 cells assessed as inhibition of fMLF-induced intracellular calcium mobilization preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed