BDBM50604354 CHEMBL5185699

SMILES Cn1cnc2ccc(cc12)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O

InChI Key InChIKey=NIEGMNQMZGWIOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50604354   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Agios Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50604354(CHEMBL5185699)
Affinity DataIC50: 31nMAssay Description:Inhibition of MT2A in MTAP-null human HCT-116 cells after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed