BDBM50604481 CHEMBL5174660

SMILES CCn1nc(C)cc1C(=O)Nc1nc2cc(cc(OC)c2n1C\C=C\Cn1c(NC(=O)c2cc(C)nn2CC)nc2cc(cc(OCCCN)c12)C(N)=O)C(N)=O

InChI Key InChIKey=GHYYYXLQUGJICH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50604481   

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50604481(CHEMBL5174660)
Affinity DataEC50:  1.62nMAssay Description:Agonist activity at STING in human wild-type THP1-Dual cells co-expressing ISRE reporter assessed as IRF-mediated immune response incubated for 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50604481(CHEMBL5174660)
Affinity DataEC50:  10nMAssay Description:Agonist activity at STING in digitonin-permeabilized human THP1-Dual cells expressing NF-kappaB-SEAP and IRF-Lucia luciferase reporter assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed