BDBM50604615 CHEMBL5199360

SMILES CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1cn(C)c(=O)c2cc(oc12)-c1cnc([nH]1)C(C)C

InChI Key InChIKey=XPLLEGZGTOMAKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50604615   

TargetBromodomain-containing protein 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50604615(CHEMBL5199360)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of C-terminal His6-tagged BRD4 BD1 (unknown origin) using H-YSGRGK(Ac)GGK(Ac)GLGK(Ac)-GGAK(Ac)RHRK-Biotin-OH as substrate incubated for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50604615(CHEMBL5199360)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of C-terminal His6-tagged BRD4 BD2 (unknown origin) using H-YSGRGK(Ac)GGK(Ac)GLGK(Ac)-GGAK(Ac)RHRK-Biotin-OH as substrate incubated for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed