BDBM50605409 CHEMBL5209870

SMILES COc1cc(OC)c2c(c1)nc([nH]c2=O)-c1cc(C)c(OCCOc2ccccc2C(N)=O)c(C)c1

InChI Key InChIKey=LDUXKZCPPPHDPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50605409   

TargetBromodomain-containing protein 4(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50605409(CHEMBL5209870)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of BRD4 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50605409(CHEMBL5209870)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of PARP1 (unknown origin) using NAD+ as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed