BDBM50606044 CHEMBL5188347

SMILES COc1cc(cnc1OC)-c1cc2c(O[C@H]3CCN(C3)C(=O)C(C)C)ncnc2s1

InChI Key InChIKey=BEEFOOJDYHKEAX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50606044   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Peking Union Medical College

Curated by ChEMBL

LigandBDBM50606044(CHEMBL5188347)Copy SMILESCopy InChI

Affinity DataIC50: 411nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-glo luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/25/2023
Entry Details
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Peking Union Medical College

Curated by ChEMBL

LigandBDBM50606044(CHEMBL5188347)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-glo luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/25/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL