BDBM50606277 CHEMBL5206786

SMILES Cn1c(CN2CCC(CC2)c2nc(OCc3ccc(Cl)cc3F)ncc2F)nc2ccccc12

InChI Key InChIKey=FCFRZXHZSYIILV-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50606277   

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50606277(CHEMBL5206786)
Affinity DataEC50: >9.90E+3nMAssay Description:Agonist activity at human GLP-1R expressed in CHO-K1 cells assessed as cAMP accumulation incubated for 30 mins in presence of BETP by BETP sensitized...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50606277(CHEMBL5206786)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at human GLP-1R expressed in CHO-K1 cells assessed as cAMP accumulation incubated for 30 mins in absence of BETP by plate reader met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50606277(CHEMBL5206786)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at GLP-1R (unknown origin) expressed in candidate selection CHO cells assessed as cAMP accumulation incubated for 30 mins by plate r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50606277(CHEMBL5206786)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of hERG ion channel by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed