BDBM50606293 CHEMBL5171631

SMILES C[C@H]1C[C@H](O)CN(C1)c1ncc(Cl)c(Nc2ccc3n(C)c(=O)c4OCC(F)(F)[C@@H](Nc4c3c2)C2CC2)n1

InChI Key InChIKey=GSGDUDAFETZSPM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50606293   

TargetB-cell lymphoma 6 protein(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50606293(CHEMBL5171631)
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal thioredoxin-His6 tagged human BCL6 BTB domain (5 to 129 residues) expressed in Escherichia coli BL21-AI incubated for 2 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetB-cell lymphoma 6 protein(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50606293(CHEMBL5171631)
Affinity DataEC50: >2.00E+3nMAssay Description:Degradation of BCL6 in human OCI-Ly1 cells incubated for 2 hrs by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed