BDBM50606833 CHEMBL5219483

SMILES CC1CCCC(C)N1C(=S)SCCCCOc1ccc2c(C)c(Cl)c(=O)oc2c1

InChI Key InChIKey=IKYVMKQIWKXWDL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50606833   

TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606833(CHEMBL5219483)
Affinity DataIC50: 114nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured upto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606833(CHEMBL5219483)
Affinity DataIC50: 5.85E+3nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured upto 20 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606833(CHEMBL5219483)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured upto 20 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50606833(CHEMBL5219483)
Affinity DataIC50: 114nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 6 mins followed by substrate addition by DTNB reagent based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606833(CHEMBL5219483)
Affinity DataIC50: 101nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate incubated for 15 mins followed by substrate addition and measured upto 20 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed