BDBM50607034 CHEMBL5218472

SMILES Nc1nc(N)c(C#N)c(n1)N1CC2(CC2)C[C@H]1c1nc2cccc(Cl)c2c(=O)n1Cc1ccc(s1)C(=O)NO

InChI Key InChIKey=UBELCIYBIARHIU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50607034   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50607034(CHEMBL5218472)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of PI3Kdelta (unknown origin) measured by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50607034(CHEMBL5218472)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6 (unknown origin) measured by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50607034(CHEMBL5218472)
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC1 (unknown origin) measured by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50607034(CHEMBL5218472)
Affinity DataIC50: 169nMAssay Description:Inhibition of PI3Kalpha (unknown origin) measured by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50607034(CHEMBL5218472)
Affinity DataIC50: 31nMAssay Description:Inhibition of PI3Kgamma (unknown origin) measured by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50607034(CHEMBL5218472)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) measured by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50607034(CHEMBL5218472)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of HDAC11 (unknown origin) measured by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed