BDBM50607146 CHEMBL5220833

SMILES NC1CCCC(C1)NS(=O)(=O)c1ccc(cc1)-c1ccc(CSc2nc3CCCc3c(=O)[nH]2)cc1

InChI Key InChIKey=MDTVXTHPTRFSHT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50607146   

TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607146(CHEMBL5220833)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607146(CHEMBL5220833)
Affinity DataIC50: 832nMAssay Description:Inhibition of MMP-2 (unknown origin) using fTHP-15(FAM) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607146(CHEMBL5220833)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of MMP-8 (unknown origin) using fTHP-15(FAM) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed