BDBM50607610 CHEMBL2359411::US11718589, Compound 7b

SMILES CCNC(=O)c1ccc2nc(-c3ccccc3)c(nc2c1)-c1ccccc1

InChI Key InChIKey=GDHPYSGYFQPVIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607610   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50607610(CHEMBL2359411 | US11718589, Compound 7b)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 15-PGDH (unknown origin) using NAD as substrate measured for 3.5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50607610(CHEMBL2359411 | US11718589, Compound 7b)
Affinity DataIC50: 2.50E+3nMAssay Description:This Example provides data on two groups (Table 1 and Table 2) of structural analogues of identified 15-PGDH inhibitors. Data provided is the IC50 of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent