BDBM50607649 CHEMBL5219985::US11718589, Compound 84b

SMILES CCOC(=O)Cn1ccc2cc(ccc2c1=O)-c1cnc2ccc(cc2n1)C(=O)N1CCCCC1

InChI Key InChIKey=PUCPSQNYZKOCPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607649   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM50607649(CHEMBL5219985 | US11718589, Compound 84b)
Affinity DataIC50: 4.80nMAssay Description:This Example provides data on two groups (Table 1 and Table 2) of structural analogues of identified 15-PGDH inhibitors. Data provided is the IC50 of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
Go to US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM50607649(CHEMBL5219985 | US11718589, Compound 84b)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of 15-PGDH (unknown origin) using NAD as substrate measured for 3.5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed