BDBM50607978 CHEMBL5276750

SMILES CC#Cc1cncc(c1)-c1ccc2OC[C@@]3(N=C(N)C[C@H]3C(F)(F)F)c2c1

InChI Key InChIKey=QXBFTWSGJHVMLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50607978   

TargetBeta-secretase 1(Human)
Rmit University

Curated by ChEMBL
LigandPNGBDBM50607978(CHEMBL5276750)
Affinity DataIC50: 115nMAssay Description:Inhibition of human BACE1 (1 to 454 residues) using APP harboring Swedish Lys/Met mutant-derived peptide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed