BDBM50607981 CHEMBL4782984

SMILES [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(=O)OCC#C

InChI Key InChIKey=ZWZUCWWQSRNAKQ-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50607981   

TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50607981(CHEMBL4782984)
Affinity DataKd:  900nMAssay Description:Binding affinity to human recombinant caspase 3 at 0.3125 to 5 uM measured after 400 secs by Surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50607981(CHEMBL4782984)
Affinity DataIC50: 1.70E+3nMAssay Description:Disruption of His-tagged full length HSP90 (unknown origin)/GST-tagged Cdc37 (unknown origin) measured after 1 hr by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50607981(CHEMBL4782984)
Affinity DataEC50:  1.80E+3nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed