BDBM50608579 CHEMBL5279294

SMILES Cc1noc(C)c1-c1ccc2n(CCCCCCC(=O)NO)cc(Cc3cccc(c3)C(F)(F)F)c2c1

InChI Key InChIKey=ZEWRQBNFEANYQN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50608579   

TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608579(CHEMBL5279294)
Affinity DataIC50: 13nMAssay Description:Inhibition of human HDAC3 using human HeLa cell nuclear extract at 1 uM measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608579(CHEMBL5279294)
Affinity DataIC50: 31nMAssay Description:Inhibition of human HDAC1 using human HeLa cell nuclear extract at 1 uM measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608579(CHEMBL5279294)
Affinity DataIC50: 79nMAssay Description:Inhibition of human HDAC2 using human HeLa cell nuclear extract at 1 uM measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed