BDBM50608716 CHEMBL5269322

SMILES OS(=O)(=O)Oc1cc(OCCOc2cc(ccc2OS([O-])(=O)=O)-c2oc3cc(OS([O-])(=O)=O)cc(OCCOc4cc(OS([O-])(=O)=O)cc5oc(-c6ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c6)c(OS([O-])(=O)=O)c(=O)c45)c3c(=O)c2OS([O-])(=O)=O)c2c(c1)oc(-c1ccc(OS(O)(=O)=O)c(OS([O-])(=O)=O)c1)c(OS([O-])(=O)=O)c2=O

InChI Key InChIKey=WAMIOPNMAFDILS-UHFFFAOYSA-E

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50608716   

TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50608716(CHEMBL5269322)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of human coagulation factor XIIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50608716(CHEMBL5269322)
Affinity DataKd:  2.53E+4nMAssay Description:Binding affinity to human coagulation factor XIIIa by Spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XIII A chain [Q652E](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50608716(CHEMBL5269322)
Affinity DataIC50: 7.63E+4nMAssay Description:Inhibition of human coagulation factor XIIIa assessed as inhibition of factor 13a mediated fibrin polymerization incubated for 24 hrs by SDS-PAGE ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed