BDBM50609601 CHEMBL5266482

SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1cn2CCCc3cccc1c23

InChI Key InChIKey=NYQYOLFXHDNNEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50609601   

TargetEpidermal growth factor receptor(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50609601(CHEMBL5266482)
Affinity DataIC50: 71nMAssay Description:Inhibition of EGR-induced EGFR phosphorylation in human A549 cells pretreated for 2 hrs followed by EGF stimulation by immune assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed