BDBM50609669 CHEMBL5288393

SMILES CCCOc1ccc(NC(=O)C(C)(C)c2csc(NS(=O)(=O)C3CC3)n2)cc1

InChI Key InChIKey=BOEWQRNBSGZWMC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50609669   

TargetCTP synthase 1(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609669(CHEMBL5288393)
Affinity DataIC50: 3.83E+5nMAssay Description:Inhibition of C-terminal FLAG-His8-tagged full length human CTPS1 preincubated for 10 mins followed by substrate addition by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCTP synthase 2(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609669(CHEMBL5288393)
Affinity DataIC50: 710nMAssay Description:Inhibition of human CTPS2 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCTP synthase 1(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609669(CHEMBL5288393)
Affinity DataIC50: 580nMAssay Description:Inhibition of human CTPS1 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCTP synthase 2(Rat)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609669(CHEMBL5288393)
Affinity DataIC50: 235nMAssay Description:Inhibition of rat CTPS2 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCTP synthase 2(Mouse)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609669(CHEMBL5288393)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of mouse CTPS2 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCTP synthase 1(Mouse)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609669(CHEMBL5288393)
Affinity DataIC50: 440nMAssay Description:Inhibition of mouse CTPS1 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed