BDBM50609838 CHEMBL5278656

SMILES COc1cccc(c1)S(=O)(=O)n1ccc2cnc(Nc3ccc(cc3)N3C[C@H](C)N[C@H](C)C3)nc12

InChI Key InChIKey=GLRBJDQXLPBXND-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50609838   

TargetFibroblast growth factor receptor 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609838(CHEMBL5278656)
Affinity DataIC50: 17nMAssay Description:Inhibition of FGFR4 (unknown origin) using TK as substrate incubated for 1 hr in presence of biotin/ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609838(CHEMBL5278656)
Affinity DataIC50: 30nMAssay Description:Inhibition of FGFR3 (unknown origin) using TK as substrate incubated for 1 hr in presence of biotin/ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609838(CHEMBL5278656)
Affinity DataIC50: 47nMAssay Description:Inhibition of FGFR2 (unknown origin) using TK as substrate incubated for 1 hr in presence of biotin/ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609838(CHEMBL5278656)
Affinity DataIC50: 64nMAssay Description:Inhibition of FGFR1 (unknown origin) using TK as substrate incubated for 1 hr in presence of biotin/ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed