BDBM50610150 CHEMBL5281604

SMILES FC(F)(F)c1cc(cc(C(=O)Nc2ccccc2)c1Cl)C(=O)NCc1ccccc1

InChI Key InChIKey=ZIZWFKJJDPNAKL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50610150   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50610150(CHEMBL5281604)
Affinity DataEC50:  2.20E+3nMAssay Description:Inverse agonist activity at GST tagged human PPARgamma LBD (231 to 505 residues) expressed in Escherichia coli BL21(DE3) assessed as recruitment of f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50610150(CHEMBL5281604)
Affinity DataIC50: 5.00E+3nMAssay Description:Inverse agonist activity at human PPARgamma in human RT112/84 transfected with NLuc-fused FABP4 assessed as reduction in PPARgamma transactivation in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed