BDBM50610158 CHEMBL5291018

SMILES Fc1ccc(CNC(=O)c2cc(C(=O)Nc3ccccn3)c(Cl)cc2F)cc1F

InChI Key InChIKey=NYJLLRCXLMMGDE-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50610158   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50610158(CHEMBL5291018)
Affinity DataIC50: 54nMAssay Description:Inverse agonist activity at human PPARgamma in human RT112/84 transfected with NLuc-fused FABP4 assessed as reduction in PPARgamma transactivation in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50610158(CHEMBL5291018)
Affinity DataEC50:  110nMAssay Description:Inverse agonist activity at GST tagged human PPARgamma LBD (231 to 505 residues) expressed in Escherichia coli BL21(DE3) assessed as recruitment of f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed