BDBM50610520 CHEMBL5268100

SMILES CCOc1cc(O)c(cc1CN1CCC=C(C1)C1C(=O)Nc2ccccc12)C(=O)\C=C\c1ccc(Cl)cc1Cl

InChI Key InChIKey=LNJYAGKLYNUXFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50610520   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50610520(CHEMBL5268100)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of wildtype SHP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50610520(CHEMBL5268100)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of SHP2 (unknown origin) E76K mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed