BDBM50610588 CHEMBL5269562

SMILES O=C(Nc1ccc(NC(=O)c2ccc(Nc3ccnc4ccccc34)cc2)cc1)OCc1ccccc1

InChI Key InChIKey=IYMVVPRGHKLCCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50610588   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610588(CHEMBL5269562)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of human recombinant full-length N-terminal GST tagged DNMT1 (2 to 1632 residues) expressed in Sf9 insect cells using poly(dI-dC) as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610588(CHEMBL5269562)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant DNMT3A (214 to 912 residues)expressed in Sf9 insect cells using lambda DNA as substrate by scintillation/filter plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed