BDBM50610937 CHEMBL5272661

SMILES CC(C)CC(=O)c1ccc(CCCN2[C@@H](CC[C@@H](O)Cc3cccc(c3)C(F)(F)F)CCC2=O)s1

InChI Key InChIKey=SHPLALYCOYXIBQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50610937   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Chengdu Sport University

Curated by ChEMBL
LigandPNGBDBM50610937(CHEMBL5272661)
Affinity DataIC50: 2nMAssay Description:Agonist activity at human EP4 receptor expressed in CHO cells co-transfected with CRE-beta-lactamase reporter gene assessed as increase in intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Chengdu Sport University

Curated by ChEMBL
LigandPNGBDBM50610937(CHEMBL5272661)
Affinity DataKi: <2nMAssay Description:Displacement of [3H]-PGE2 from human EP4 receptor transfected with HEK293 cells assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed