BDBM50611807 CHEMBL5286659

SMILES CC(C)NC(=O)c1cccc(NC(=O)Nc2ccc(c(F)c2)-c2ncnc3[nH]cc(C)c23)c1

InChI Key InChIKey=UIVVRYOORUQDIX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50611807   

TargetRho-associated protein kinase 2(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50611807(CHEMBL5286659)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant ROCK2 by ADP glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50611807(CHEMBL5286659)
Affinity DataIC50: 7.81E+5nMAssay Description:Inhibition of ROCK2 (unknown origin) by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50611807(CHEMBL5286659)
Affinity DataIC50: 7.81E+5nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed