BDBM50612149 CHEMBL5284383

SMILES [H][C@@]12CC[C@@H](O)N([C@@H](Cc3ccccc3)C(=O)N(C)[C@@H](Cc3ccc(O)cc3)C(=O)N[C@@H](C(C)C)C(=O)O[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)C\C(C)=C\Cl)[C@@H](C)CC)C(=O)N\C(=C/C)C(=O)N1)C2=O

InChI Key InChIKey=CWLDDHHTMAJFMM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50612149   

TargetNeutrophil elastase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50612149(CHEMBL5284383)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of elastase in human neutrophil using MeOSuc-AAPV-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50612149(CHEMBL5284383)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant kallikrein 7 (23 to 252 residues) using MCA-RPKPVE-Nval-WRK(Dnp)-NH2 as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil elastase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50612149(CHEMBL5284383)
Affinity DataIC50: 44nMAssay Description:Inhibition of elastase in human neutrophil using N-(OMe-succinyl)-Ala-Ala-Pro-Val-p-nitroanilide as substrate preincubated with enzyme for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed