BDBM50612189 CHEMBL5281595

SMILES CN1CCC(CC1)n1cc(Nc2nc(OC3(C)CC3)c3nc(ccc3n2)-c2ccnnc2)cn1

InChI Key InChIKey=MAXYLZJMEDMWHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612189   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50612189(CHEMBL5281595)
Affinity DataIC50: 1nMAssay Description:Inhibition of IRAK4 (unknown origin) in presence of ATP by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50612189(CHEMBL5281595)
Affinity DataIC50: 130nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed