BDBM50612197 CHEMBL5290338

SMILES [H][C@]12CN(C)[C@]([H])(C[C@H]1n1cc(Nc3nc(OC4(C)CC4)c4nc(c(F)cc4n3)-c3cnc(C)nc3)cn1)C2

InChI Key InChIKey=REFNAHFTYXTJKI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612197   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50612197(CHEMBL5290338)
Affinity DataIC50: 4nMAssay Description:Inhibition of IRAK4 (unknown origin) in presence of ATP by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50612197(CHEMBL5290338)
Affinity DataIC50: 310nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed