BDBM50612752 CHEMBL5273994

SMILES COc1cc2c(Nc3ccc(Oc4ccc(Br)cc4)cc3)ncnc2cc1OCC1CCN(C)CC1

InChI Key InChIKey=ZNKKGRMRTKXYDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50612752   

TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612752(CHEMBL5273994)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed