BDBM50612755 CHEMBL5277339

SMILES COc1cc2c(Nc3ccc(Oc4ccc(cc4)C#N)cc3)ncnc2cc1OCC1CCN(C)CC1

InChI Key InChIKey=QYVRLNJVUFPVOI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50612755   

TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612755(CHEMBL5277339)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed