BDBM50613486 CHEMBL5281790

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H]2CCC(=O)N2)C(=O)N1)C(=O)N[C@H]1CSSC[C@H](NC1=O)C(N)=O

InChI Key InChIKey=HLUXTGTURXBMGU-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50613486   

TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613486(CHEMBL5281790)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613486(CHEMBL5281790)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613486(CHEMBL5281790)
Affinity DataEC50:  5.86E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as ERK phosphorylation incubated for 2 hrs by Alphascreen surefire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed