BDBM50613609 CHEMBL5267495

SMILES [H][C@@]1(C[C@@](O)([C@H](C)NC(=O)c2[nH]c(C)c(Cl)c2Cl)[C@H](O)[C@@H](C)O1)O[C@@H]1CCC(=C)[C@]2([H])[C@H]([C@@H](C)CC[C@@]12[H])C(\O)=C1/C(=O)[C@H](C(C)C)N([C@@H]2O[C@@H](C)[C@@H](OC(N)=O)[C@@H](OC(C)=O)[C@H]2OC)C1=O

InChI Key InChIKey=NTNKQRBKOGURQE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50613609   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sbs Pharma Consulting

Curated by ChEMBL
LigandPNGBDBM50613609(CHEMBL5267495)
Affinity DataIC50: 11nMAssay Description:Inhibition of Escherichia coli DNA gyrase ATPase activity assessed as decrease in release of inorganic phosphate using kinetoplast DNA as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sbs Pharma Consulting

Curated by ChEMBL
LigandPNGBDBM50613609(CHEMBL5267495)
Affinity DataIC50: 500nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kinetoplast DNA as substrate after 30 mins in presence of potassi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sbs Pharma Consulting

Curated by ChEMBL
LigandPNGBDBM50613609(CHEMBL5267495)
Affinity DataIC50: 9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity using relaxed pBR322 DNA as substrate after 30 mins in presence of potassium glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sbs Pharma Consulting

Curated by ChEMBL
LigandPNGBDBM50613609(CHEMBL5267495)
Affinity DataIC50: 60nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activity using relaxed pBR322 DNA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed