BDBM50614580 CHEMBL5269627

SMILES [O-]S(=O)(=O)c1cc(ccc1\C=C\c1ccc(cc1S([O-])(=O)=O)N=[N+]=[N-])N=[N+]=[N-]

InChI Key InChIKey=XHPWRTXYJFNZAW-UHFFFAOYSA-L

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50614580   

TargetDNA repair protein RAD51 homolog 1(Human)
Nantes Universite

Curated by ChEMBL
LigandPNGBDBM50614580(CHEMBL5269627)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RAD51 (unknown origin) assessed as reduction in novel 58/33-dsDNA formation incubated for 1 hr by electrophoresis based DNA strand exch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDNA repair protein RAD51 homolog 1(Human)
Nantes Universite

Curated by ChEMBL
LigandPNGBDBM50614580(CHEMBL5269627)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of RAD51 (unknown origin) using labeled 100-ss DNA as substrate assessed as reduction in DNA D-loop formation by [gamma-32P]ATP based scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDNA repair protein RAD51 homolog 1(Human)
Nantes Universite

Curated by ChEMBL
LigandPNGBDBM50614580(CHEMBL5269627)
Affinity DataIC50: 4.43E+4nMAssay Description:Inhibition of wild type human RAD51 expressed in Escherichia coli BL21-DE3 using 100 bp ssDNA probe as substrate assessed as prevention of D-loop for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed