BDBM50617063 CHEMBL5408678

SMILES OC(=O)c1cc(F)c(F)cc1NC(=O)c1ccc(nn1)-n1ccc(c1)C#N

InChI Key InChIKey=NDEZZQVEDHLZHD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617063   

TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617063(CHEMBL5408678)
Affinity DataEC50:  1.05E+4nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617063(CHEMBL5408678)
Affinity DataEC50:  1.05E+4nMAssay Description:Agonist activity at STING in PMA-differentiated wildtype human THP1-Blue ISG cells harboring IRF-inducible SEAP reporter construct incubated for 24 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed