BDBM50618108 CHEMBL5403504

SMILES COc1cccnc1N1CCN(CCCc2nc3ccccc3s2)CC1

InChI Key InChIKey=BSQJXUKPWMUTBT-UHFFFAOYSA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50618108   

TargetD(2) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50618108(CHEMBL5403504)
Affinity DataIC50: 185nMAssay Description:Antagonist activity at human D2 receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50618108(CHEMBL5403504)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human D4 receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50618108(CHEMBL5403504)
Affinity DataIC50: 414nMAssay Description:Antagonist activity at human D2 receptor stably expressed in CHO-K1 cells assessed as beta arrestin recruitment preincubated for 90 mins by tropix-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50618108(CHEMBL5403504)
Affinity DataIC50: 474nMAssay Description:Antagonist activity at human D3 receptor stably expressed in CHO-K1 cells assessed as beta arrestin recruitment preincubated for 90 mins by tropix-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50618108(CHEMBL5403504)
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at human D4 receptor stably expressed in CHO-K1 cells assessed as beta arrestin recruitment preincubated for 90 mins by tropix-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50618108(CHEMBL5403504)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor stably expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50618108(CHEMBL5403504)
Affinity DataKi:  288nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor stably expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50618108(CHEMBL5403504)
Affinity DataKi:  519nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor stably expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed