BDBM50618162 CHEMBL5399923

SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)[C@H](CC)[C@]4([H])CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCOS([O-])(=O)=O

InChI Key InChIKey=ZBDVQSVMKUUOPF-UHFFFAOYSA-M

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50618162   

TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50618162(CHEMBL5399923)
Affinity DataEC50:  80nMAssay Description:Agonist activity at glutathione transferase-tagged human FXR ligand binding domain assessed as biotinylated Src1 peptide recruitment incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50618162(CHEMBL5399923)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at TGR5 receptor in human NCI-H716 cells assessed as activation of intracellular cAMP production incubated for 1 hr by HTR-FRET assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed