BDBM50618607 CHEMBL5425418

SMILES CNc1ncc2cc(-c3cc(F)ccc3F)c(=O)n(CCCCN)c2n1

InChI Key InChIKey=VCZDFACOFNRTMG-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50618607   

TargetSerine/threonine-protein kinase SIK3(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 18nMAssay Description:Inhibition of full length NanoLuc fused SIK3 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 72nMAssay Description:Inhibition of full length NanoLuc fused SIK1 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 89nMAssay Description:Inhibition of full length NanoLuc fused SIK2 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEphrin type-A receptor 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 145nMAssay Description:Inhibition of full length NanoLuc fused EPHA1 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEphrin type-B receptor 4(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 607nMAssay Description:Inhibition of full length NanoLuc fused EPHB4 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEphrin type-B receptor 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 632nMAssay Description:Inhibition of full length NanoLuc fused EPHB1 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEphrin type-A receptor 4(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of full length NanoLuc fused EPHA4 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEphrin type-A receptor 2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of full length NanoLuc fused EPHA2 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEphrin type-A receptor 3(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of full length NanoLuc fused EPHA3 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEphrin type-B receptor 3(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of full length NanoLuc fused EPHB3 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEphrin type-B receptor 2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of full length NanoLuc fused EPHB2 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of full length NanoLuc fused JNK1 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 2.81E+4nMAssay Description:Inhibition of full length NanoLuc fused ABL1 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 3.38E+4nMAssay Description:Inhibition of full length NanoLuc fused GAK (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of full length NanoLuc fused RSK1b (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed