BDBM50618708 CHEMBL4071130

SMILES Oc1cc(O)c(\C=N\NC(=O)c2cc3ccccc3cc2O)cc1O

InChI Key InChIKey=UAXHPUSKEWEOAP-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50618708   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50618708(CHEMBL4071130)
Affinity DataIC50: 560nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCrossover junction endonuclease MUS81(Homo sapiens)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50618708(CHEMBL4071130)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human GST-tagged MUS81-ECE2 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50618708(CHEMBL4071130)
Affinity DataKd:  6.10nMAssay Description:Binding affinity to human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells assessed as dissociation constant by Surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCrossover junction endonuclease MUS81(Homo sapiens)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50618708(CHEMBL4071130)
Affinity DataKd:  6.10nMAssay Description:Binding affinity to human GST-tagged MUS81-ECE2 expressed in Escherichia coli BL21(DE3)Rosetta2 cells assessed as dissociation constant by Surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed