BDBM50619112 CHEMBL5429688

SMILES CCCCS(=O)(=O)NCc1ccc(Nc2ncc(C)c(n2)-c2cnn(c2)C(C)C)cc1

InChI Key InChIKey=HGTHLADJAXIWDU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50619112   

TargetTyrosine-protein kinase JAK2(Human)
The Affiliated Hospital of Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50619112(CHEMBL5429688)
Affinity DataIC50: 421nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Mouse)
The Affiliated Hospital of Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50619112(CHEMBL5429688)
Affinity DataIC50: 182nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Affiliated Hospital of Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50619112(CHEMBL5429688)
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of FLT3 in human MOLM-13 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed