BDBM50619383 CHEMBL5435378

SMILES CC12C3C(C(=O)N(CCCCN4CCN(CC4)c4ccccc4Cl)C3=O)C(C)(C1=O)C(=C2c1ccccc1)c1ccccc1

InChI Key

Data  2 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50619383   

Target5-hydroxytryptamine receptor 1A(Rat)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50619383(CHEMBL5435378)
Affinity DataEC50:  100nMAssay Description:Agonist activity at Sprague-Dawley rat hippocampal membrane 5-HT1A receptor assessed as stimulation of [35S]GTPgammaS binding measured after 90 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50619383(CHEMBL5435378)
Affinity DataIC50: 8.40E+3nMAssay Description:Antagonist activity at Sprague-Dawley rat striatum membrane D2 receptor assessed as inhibition of dopamine stimulated [35S]GTPgammaS binding measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50619383(CHEMBL5435378)
Affinity DataEC50:  100nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat 5-HT2A receptor measured after 60 mins by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistamine H1 receptor(Rat)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50619383(CHEMBL5435378)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]pyrilamine from Sprague-Dawley rat H1 receptor assessed as inhibition constant measured after 30 mins by competitive binding assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50619383(CHEMBL5435378)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat 5-HT2A receptor assessed as inhibition constant measured after 60 mins by competitive binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed