BDBM50620823 CHEMBL5423337

SMILES CN(CCOCCN1c2ccccc2Sc2ccccc12)C(CCN)C(=O)NCc1ccccc1Cl

InChI Key InChIKey=YHPOZYSNXJXRBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50620823   

TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50620823(CHEMBL5423337)
Affinity DataIC50: 411nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50620823(CHEMBL5423337)
Affinity DataIC50: 5.17E+3nMAssay Description:Inhibition of human recombinant BACE1 using Rh-EVNLDAEFK-quencher as substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed