BDBM50621052 CHEMBL5434467

SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3cc4N(CCc4cc3OC)C(=O)CN(CC)CC)ncc2N(C)C1=O

InChI Key InChIKey=ZANSQRVTKCXEOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50621052   

TargetSerine/threonine-protein kinase PLK1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621052(CHEMBL5434467)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of PLK1 (unknown origin) preincubated for 10 mins followed by substrate and ATP addition and measured after 60 mins by ADP-Glo kinase assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621052(CHEMBL5434467)
Affinity DataIC50: 549nMAssay Description:Inhibition of BRD4 (unknown origin) using BET peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed